Anti Cancer Tablets

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Dasatinib is used to treat a certain type of chronic myeloid leukemia (CML; a type of cancer of the white blood cells) as a first treatment and in people who can no longer benefit from other leukemia medications including imatinib (Gleevec) or in those who cannot take these medications because of side effects.

Additional Information:

• Item Code: 6531
• Production Capacity: 1 year
• Delivery Time: 2-5 working days
• Packaging Details: boxes

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Sunitinib is used to treat gastrointestinal stromal tumors (GIST; a type of tumor that grows in the stomach, intestine (bowel), or esophagus (tube that connects the throat with the stomach) in people with tumors that were not treated successfully with imatinib (Gleevec) or people who cannot take imatinib.

Additional Information:

• Item Code: 02568
• Production Capacity: 1000
• Delivery Time: 1-7 working days
• Packaging Details: Box

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enofovir Alafenamide UsesTenofovir Alafenamide is used in the treatment of chronic hepatitis B virus (HBV) infection.How Tenofovir Alafenamide worksTenofovir Alafenamide is an antiviral medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection.Common side effects of Tenofovir AlafenamideHeadache

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What is Fempro used for?Fempro Tablet is an aromatase inhibitor. It is generally prescribed to treat breast cancer in women who no longer have periods, either due to menopause or after surgery or chemotherapy. It is also used to treat infertility caused due to anovulation (during menstrual cycle egg cell from ovaries is not released).

Product Details:

Sunitinib is used to treat gastrointestinal stromal tumors (GIST; a type of tumor that grows in the stomach, intestine (bowel), or esophagus (tube that connects the throat with the stomach) in people with tumors that were not treated successfully with imatinib (Gleevec) or people who cannot take imatinib.

Product Details:

Olumiant (baricitinib) is used for the treatment of adult patients with active rheumatoid arthritis, who already have had an inadequate response to one or more tumor necrosis factor (TNF) antagonist therapies. Baricitinib blocks the activity of certain enzymes that are involved in activating inflammation in the body. Olumiant 2 mg tablet is light pink, debossed with “Lilly” on one side and “2” on the other. Olumiant 4 mg tablet is light pink, debossed with “Lilly” on one side and “4” on the other. 

Baricitinib is a selective and reversible Janus kinase 1 (JAK1) and 2 (JAK2) inhibitor. Janus kinases belong to the tyrosine protein kinase family. They play a crucial role in the proinflammatory pathway signalling that is frequently over-activated in rheumatoid arthritis. By blocking the actions of JAK1/2, baricitinib works to disrupt the activation of downstream signalling molecules and proinflammatory mediators. 

Pharmacodynamics 
Baricitinib inhibition of IL-6 induced STAT3 phosphorylation 

Baricitinib administration resulted in a dose-dependent inhibition of IL-6 induced STAT3 phosphorylation in whole blood from healthy subjects with maximal inhibition observed approximately 1 hour after dosing, which returned to near baseline by 24 hours. Similar levels of inhibition were seen using either IL-6 or TPO as the stimulus. 

Immunoglobulins 
Mean serum IgG, IgM, and IgA values decreased by 12 weeks after starting treatment with Olumiant, and remained stable through at least 52 weeks. For most patients, changes in immunoglobulins occurred within the normal reference range.  

C-reactive protein 
In patients with rheumatoid arthritis, decreases in serum C-reactive protein (CRP) were observed as early as one week after starting treatment with Olumiant and were maintained throughout dosing.  

Cardiac Electrophysiology 
At a dose 10 times the maximum recommended dose, baricitinib does not prolong the QT interval to any clinically relevant extent. 

Ingredients 
The active ingredient in Olumiant is Baricitinib. Other ingredients are croscarmellose sodium, magnesium stearate, mannitol, microcrystalline cellulose, iron oxide red, lecithin, macrogol 3350, polyvinyl alcohol, purified talc and titanium dioxide. 

Usage Of Olumiant (Baricitinib) 
Olumiant (baricitinib) is used for the treatment of adult patients with active rheumatoid arthritis, who already have had an inadequate response to one or more tumor necrosis factor (TNF) antagonist therapies.